Recent research has revealed that the pancreas is not alone in determining how much insulin is released. A newly discovered hormone which is found in the liver can promote the growth of more insulin cells in the Islets of Langerhans region of the pancreas.
Researchers at the Harvard Stem Cell Institute in Cambridge, Massachusetts, identified the new hormone, betatrophin, by creating insulin resistance in mice. When the mice experienced insulin resistance they started the develop more of the insulin-secreting pancreatic β cells.
The researchers, led by Douglas Melton, then painstakingly sought out the reason for the new growth of cells. Eventually they singled out the new hormone in the liver.
This finding was followed by further experiments to test the results by injecting mice with betatrophin. The result was around 17 times more cells were grown than is normal. The same hormone is also found in the human liver.
The betatrophin hormone is only active in the pancreas. The slowing of the development of new Pancreatic β cells is the cause of type 2 diabetes. This new hormone could lead to a new treatment for diabetes.
Liver hormone offers hope for diabetes treatment by Chris Palmer, 25 April 2013. Nature.com. doi:10.1038/nature.2013.12878
With careful management a person with Type 1 Diabetes can lead a healthy and full life. Type 1 Diabetes develops when insulin production slows or stops and treatment is by means of insulin injections. This is a daunting prospect for … read more
(advertisement) The treatment of diabetes is expected to cost the National Health Service in excess of £16.9 bn annually by 2035 and may potentially “bankrupt” the service due to the continually growing number of people being diagnosed with the condition … read more
Many people tend to overlook the fact that skin is the largest organ in the body, and just as you would care for your other organs you should also care for your skin. Proper skin care is important for everyone, … read more
New research has indicated that a high fat diet may be a possible cause of the onset of type 2 diabetes. For a long time there has been a known connection between obesity and the development of type 2 diabetes … read more
If you do not have diabetes then you should be aware at least of the 4 main risk factors which could result in you developing the disease later in life. Being overweight Lack of Exercise Being Asian or African Family … read more
This is the first of the myths of diabetes which have been plaguing attempts to raise awareness of the disease. Yes, there are several types of diabetes. Type 1 and Type 2 diabetes are the most common forms, and the … read more